Cornu, I.; Syntrivanis, L-D.; Tiefenbacher, K.*
Nat Protoc, 2023,
“Biomimetic tail-to-head terpene cyclizations using the resorcin[4]arene capsule catalyst”



Klucznik, T.; Syntrivanis, L.-D.; Baś, S.; Mikulak-Klucznik, B.; Moskal, M.; Szymkuć, S.; Mlynarski, J.; Gadina, L.; Beker, W.; Burke, M.; Tiefenbacher, K.; Grzybowski, B.
Nature, 2023, Accelerated Article Preview.
“Computational Prediction of Complex Cationic Rearrangement Outcomes”



Schmid, D.; Li, T-R.; Goldfuss, B.; Tiefenbacher, K.*
J. Org. Chem. 2023, Article ASAP.
“Exploring the Glycosylation Reaction Inside the Resorcin[4]arene Capsule”


Zenka, M.; Preinl, J.; Pertermann, E.; Lützen, A.; Tiefenbacher, K.*
Eur. J. Inorg. Chem. 2023, 26, e202300110.
“A Water- and Base-Stable Iminopyridine-Based Cage That Can Bind Larger Organic Anions”


Li, T-R.; Piccini, G. M.; Tiefenbacher, K.*
J. Am. Chem. Soc. 2023, 145, 4294-4303.
“Supramolecular Capsule-Catalyzed Highly β-Selective Furanosylation Independent of the SN1/SN2 Reaction Pathway”


Némethová, I.; Schmid, D.; Tiefenbacher, K.*
Angew. Chem. Int. Ed. 2023, e202218625.
“Supramolecular Capsule Catalysis Enables the Exploration of Terpenoid Chemical Space Untapped by Nature”




Chen, H.; Li, T-R.; Sakai, N.; Besnard, C.; Guénée, L.; Pupier, M.; Viger-Gravel, J.; Tiefenbacher, K.; Matile, S.*
Chem. Sci. 2022, 13, 10273.
“Decoded fingerprints of hyperresponsive, expanding product space: polyether cascade cyclizations as tools to elucidate supramolecular catalysis”



Pfeuffer-Rooschüz, J.; Heim, S.; Prescimone, A.; Tiefenbacher, K.*
Angew. Chem. Int. Ed. 2022, 61, e202209885.
“Megalo-Cavitands: Synthesis of Acridane[4]arenes and Formation of Large, Deep Cavitands for Selective C70 Uptake”
(highlighted in C&EN, 2022, 100, 33.)


Li, T-R.; Huck, F.; Piccini, G. M.; Tiefenbacher, K.*
Nat. Chem. 2022, 14, 985.
“Mimicry of the proton wire mechanism of enzymes inside a supramolecular capsule enables β-selective O-glycosylations”


Sokolova, D.; Piccini, G.M.; Tiefenbacher, K.*
Angew. Chem. Int. Ed. 2022, 61, e202203384.
“Enantioselective Tail-to-Head Terpene Cyclizations by Optically Active Hexameric Resorcin[4]arene Capsule Derivatives”


Huck, F.; Catti, L.; Reber, G.L.; Tiefenbacher, K.*
J. Org. Chem. 2022, 87, 419.
“Expanding the Protecting Group Scope for the Carbonyl Olefin Metathesis Approach to 2,5-Dihydropyrroles”


Pfeuffer-Rooschüz, J.; Schmid, L.; Prescimone, A.; Tiefenbacher, K.*
JACS Au 2021, 11, 1885.
“Xanthene[n]arenes: Exceptionally Large, Bowl-shaped Macrocyclic Building Blocks Suitable for Self-Assembly”




Hao, X.; Li, T-R.; Chen, H.; Gini, A.; Zhang, X.; Rosset, S.; Mazet, C.; Tiefenbacher, K.; Matile, S.*
Chem. Eur. J. 202127, 12215.
“Bioinspired Ether Cyclizations within a π-Basic Capsule Compared to Autocatalysis on π-Acidic Surfaces and Pnictogen-Bonding Catalysts”


Nemat, S. J.; Van den Eynden, D.; Deblock, L.; Heilmann, M.; Köster, J. M.; Parvizian, M.; Tiefenbacher, K.*; De Roo, J.*
Chem. Commun., 2021, 57, 4694.
“Resorcin[4]arene-based multidentate phosphate ligands with superior binding affinity for nanocrystal surfaces”


Heilmann, M.; Knezevic, M.; Piccini, G. M.; Tiefenbacher, K.*
Org. Biomol. Chem. 2021, 19, 3628.
“Understanding the binding properties of phosphorylated glycoluril-derived molecular tweezers and selective nanomolar binding of natural polyamines in aqueous solution”


Merget, S.; Catti, L.; Zev, S.; Major, D.T.; Trapp, N.; Tiefenbacher, K.*
Chem. Eur. J. 2021, 27, 4447.
“Concentration‐dependent Self‐assembly of an Unusually Large Hexameric Hydrogen‐bonded Molecular Cage”


Némethová, I.; Syntrivanis, L.-D.; Tiefenbacher, K.*
Chimia 2020, 74, 561.
“Molecular Capsule Catalysis: Ready to Address Current Challenges in Synthetic Organic Chemistry?”



Nemat, S. J.; Jędrzejewska, H.; Prescimone, A.; Szumna, A.; Tiefenbacher, K.*
Org. Lett. 2020, 22, 5506.
“Catechol[4]arene: The Missing Chiral Member of the Calix[4]arene Family”


Knezevic, M.; Heilmann, M.; Piccini, G. M.; Tiefenbacher, K.*
Angew. Chem. Int. Ed. 202059, 12387.
“Overriding Intrinsic Reactivity in Aliphatic C–H Oxidation: Preferential C3/C4 Oxidation of Aliphatic Ammonium Substrates”


Syntrivanis, L.-D.; Némethová, I.; Schmid, D.; Levi, S.; Prescimone, A.; Bissegger, F.; Major, D. T.; Tiefenbacher, K.*
J. Am. Chem. Soc. 2020142, 5894. 
“Four-Step Access to the Sesquiterpene Natural Product Presilphiperfolan-1β-ol and Unnatural Derivatives via Supramolecular Catalysis”


Bissegger, F. R.; Neuburger, M.; Tiefenbacher, K.*
Supramolecular Chemistry 2020, 32, 32o.
“Scope of the direct trimerisation to C3-symmetric cyclotribenzylene derivatives”


Merget, S.; Catti, L.; Piccini, G. M.; Tiefenbacher, K.*
J. Am. Chem. Soc. 2020, 142, 4400.
“Requirements for Terpene Cyclizations inside the Supramolecular Resorcinarene Capsule: Bound Water and its Protonation Determine the Catalytic Activity”


Heilmann, M.; Tiefenbacher, K.*
Chem. Eur. J. 2019, 25, 12900.
“A Modulated Phosphorylated Glycoluril-Derived Molecular Tweezer for Potent Binding of Aliphatic Diamines”


Zhang, Q.; Tiefenbacher, K.*
Angew. Chem. Int. Ed. 2019, 58, 12688.
“Sesquiterpene Cyclizations inside the Hexameric Resorcinarene Capsule: Total Synthesis of δ‐Selinene and Mechanistic Studies”


Zhang, Q.; Catti, L.; Syntrivanis, L.-D.; Tiefenbacher, K.*
Nat. Prod. Rep. 2019, 36, 1619.
“En route to terpene natural products utilizing supramolecular cyclase mimetics”


Pahima, E.; Zhang, Q.; Tiefenbacher, K.; Major, D. T.
J. Am. Chem. Soc. 2019, 141, 6234.
“Discovering Monoterpene Catalysis Inside Nanocapsules with Multiscale Modeling and Experiments”


Köster, J.; Häussinger, D.; Tiefenbacher, K.*
Front. Chem
. 2019, 6, 639.
“Activation of primary and secondary benzylic and tertiary alkyl (sp3)C-F bonds inside a self-assembled molecular container”


Zhang Q.; Catti, L.; Tiefenbacher, K.*
. Chem. Res. 2018, 51, 2107.
Catalysis inside the Hexameric Resorcinarene Capsule”


Zhang, Q.; Rinkel, J.; Goldfuss, B.; Dickschat, J.; Tiefenbacher, K.*
Nat. Catal. 2018, 1, 609.
“Sesquiterpene cyclizations catalysed inside the resorcinarene capsule and application in the short synthesis of isolongifolene and isolongifolenone”
(highlighted in “News and Views” Nat. Catal. 20181, 567.)


Thamm, I.; Tiefenbacher, K.; Rychlik, M.
2018, 10, 511.
“Quantification of α-Thujone and Its Metabolites in Human Urine after Consumption of a Sage Infusion Using Stable Isotope Dilution Assays”


Köster, J.; Tiefenbacher, K.*
ChemCatChem 2018, 10, 2941.
“Elucidating the Importance of Hydrochloric Acid as a Cocatalyst for Resorcinarene-Capsule-catalyzed reactions”


Catti, L.; Tiefenbacher, K.*
Angew. Chem. Int. Ed. 2018, 57, 14589.
“Brønsted Acid-Catalyzed Carbonyl-Olefin Metathesis inside a Self-Assembled Supramolecular Host”


Bräuer, T.; Zhang, Q.; Tiefenbacher, K.* 
J. Am. Chem. Soc. 2017, 139, 17500.
“Iminium Catalysis inside a Self-Assembled Supramolecular Capsule: Scope and Mechanistic Studies”

Lou, Y.; Steib, M.; Zhang, Q.; Tiefenbacher, K.; Horvath, A.; Jentys, A.; Liu, Y.; Lercher, J. A.*
J. Catal. 2017, 356, 147.

Zhang, Q.; Catti, L.; Pleiss, J.; Tiefenbacher, K.*
J. Am. Chem. Soc. 2017, 139, 11482.
Terpene Cyclizations inside a Supramolecular Catalyst: Leaving Group-Controlled Product Selectivity and Mechanistic Studies

 27. Pollok, C. H.; Zhang, Q.; Tiefenbacher, K.; Merten, C.
ChemPhysChem 2017, 18, 1987.
“Chirality induction from a chiral guest to the hydrogen bonding network of its hexameric resorcinarene host capsule”

Richers, J.; Pöthig, A.; Herdtweck, E.; Sippel, C.; Hausch, F.; Tiefenbacher, K.*
Chem. Eur. J. 2017, 23, 3178.
“Synthesis and Neurotrophic Activity Studies of Illicium Sesquiterpene Natural Product Analogues”


Catti, L.; Pöthig, A.; Tiefenbacher, K.*
Adv. Synth. Catal. 2017, 359, 1331.
“Host-Catalyzed Cyclodehydration–Rearrangement Cascade Reaction of Unsaturated Tertiary Alcohols”

24. chemsci2017
Richers, J.; Heilmann, M.; Drees, M.; Tiefenbacher, K.*, Org. Lett. 2016, 18, 6472.


Catti L.; Bräuer T.; Zhang Q.; Tiefenbacher K.* 
Chimia 2016, 70, 810.
“Exploring Catalysis inside Self-assembled Supramolecular Containers”

Thamm, I.; Richers, J.;  Rychlik M.; Tiefenbacher, K.*
Bräuer, T.; Zhang, Q.; Tiefenbacher, K.*
Angew. Chem. Int. Ed. 2016, 55, 7698.
“Iminium Catalysis inside a Self-Assembled Supramolecular Capsule: Modulation of Enantiomeric Excess”
19. Catti, L.; Zhang, Q.; Tiefenbacher, K.*
Chem. Eur. J. 201622, 9060.
“Advantages of Catalysis in Self-Assembled Molecular Capsules”
18. Catti, L.; Zhang, Q.; Tiefenbacher, K.*
Synthesis 2016, 48, 313.
“Self-Assembled Supramolecular Structures as Catalysts for Reactions Involving Cationic Transition States”
17. Zhang, Q.; Tiefenbacher, K.*
Nature Chem. 2015, 7, 197.
“Terpene cyclization catalysed inside a self-assembled cavity”
(highlighted in “News and Views” Nature Chem. 2015, 7, 187.)
16. Catti, L.; Tiefenbacher, K.*
Chem. Commun. 2015, 51, 892.
“Intramolecular hydroalkoxylation catalyzed inside a self-assembled cavity of an enzyme-like host structure”
15. Räder, A..; Tiefenbacher, K.*
Angew. Chem. Int. Ed. 2014, 53, 1206. (Highlight)
“Tertiary Alcohols as Substrates for SN2-Like Stereoinversion”
14. Zhang, Q.; Tiefenbacher, K.*
J. Am. Chem. Soc. 2013, 135, 16213.
“Hexameric Resorcinarene Capsule is a Brønsted Acid: Investigation and Application to Synthesis and Catalysis”

Postdoc &PhD work:

 13.  Tiefenbacher, K.; Zhang, K-d.; Ajami, D.; Rebek, J.
J. Phys. Org. Chem. 2014, 28, 187.
“Robust hydrogen-bonded capsules with stability in competitive media” 
 12.  Wei, J.; Tiefenbacher, K.; Ajami, D.; Rebek, J.
Chem. Sci. 2012, 3, 3022.
“Complexes within complexes: hydrogen bonding in capsules” 
 11. Tiefenbacher, K.; Rebek, J.
J. Am. Chem. Soc. 2012, 134, 2914.
“Selective Stabilization of Self-Assembled Hydrogen-Bonded Molecular Capsules Through π-π Interactions” 
 10. Tiefenbacher, K.; Ajami, D.; Rebek, J.
Angew. Chem. Int. Ed. 2011, 50, 12003.
“Self-Assembled Capsules of Unprecedented Shapes”
(highlighted in Science 2011, 333, 1361.) 
 9. Tiefenbacher, K.; Dube, H.; Ajami, D.; Rebek, J.
Chem. Comm. 2011, 47, 7341.
“A transparent photo-responsive organogel based on a glycoluril supergelator” 
 8. Tiefenbacher, K.; Trondlin, L.; Mulzer, J.; Pfaltz, A.
Tetrahedron 2010, 66, 6508.
“An expeditious asymmetric formal synthesis of the antibiotic platensimycin” 
 7. Tiefenbacher, K.; Gollner, A.; Mulzer, J.
Chem. Eur. J. 2010, 16, 9616.
“Syntheses and Antibacterial Properties of iso-Platencin, Cl-iso-Platencin and Cl-Platencin: Identification of a New Lead Structure” 
 6.  Magauer, T.; Mulzer, J.; Tiefenbacher, K.
Org. Lett. 2009, 11, 5306.
“Total Syntheses of (+)-Echinopine A and B: Determination of Absolute Stereochemistry” 
5. Tiefenbacher, K.; Mulzer, J.
J. Org. Chem. 2009, 74, 2937.
“A Nine-Step Total Synthesis of (–)-Platencin” 
 4.  Tiefenbacher, K.; Mulzer, J.
Angew. Chem. Int. Ed. 2008, 47, 6199.
“Short Formal Synthesis of (–)-Platencin” 
3. Tiefenbacher, K.; Mulzer, J.
Angew. Chem. Int. Ed. 2008, 47, 2548.
“Synthesis of Platensimycin (Minireview)” 
2. Tiefenbacher, K.; Mulzer, J.
Angew. Chem. Int. Ed. 2007, 46, 8074.
“Protecting-Group-Free Formal Synthesis of Platensimycin” 
 1.  Tiefenbacher, K.; Arion, V. A.; Mulzer, J.
Angew. Chem. Int. Ed. 2007, 46, 2690.
“A Diels-Alder Approach to (–)-Ovalicin”